Research & Commentary Results

The evolving confrontation with Israel and the United States places the Islamic Republic of Iran at a critical inflection point. Tehran faces choices that range from limited negotiation and strategic restraint to escalation and eventual collapse. The following analysis explores the key scenarios that could unfold in the coming days, weeks, and years.

Senior Fellow Alex Vatanka joins hosts Alistair Taylor and Matthew Czekaj to examine the dramatic escalation between Israel and Iran following Israel’s targeted strikes on Iranian nuclear sites, infrastructure, and senior IRGC officials. Vatanka discusses how the Iranian regime is responding, the risk of wider regional conflict, and whether the current campaign could mark the beginning of the end for the Islamic Republic.

The past four days have clarified much about what Israel wants from this conflict, what Iran can and cannot do to fight back, and what decisions confront the American president over the next few days.

The spotlight in America this week is trained on the home front, with growing tensions inside the country over President Donald Trump’s immigration crackdown and a showdown unfolding on the streets of Los Angeles. At times like these, the rest of the world has a way of intruding, sometimes unexpectedly, and Trump 2.0’s foreign policy is still struggling to produce a major positive outcome from its frenetic activity trying to end kinetic wars while prosecuting an unprecedented economic war with much of the rest of the world.

Near-term progress in a renewed nuclear agreement between the United States and Iran could add further downward pressure to a delicate oil market, potentially heralding more fiscal pain for Gulf oil producers and complicating US energy strategy.

The harsh realities of the region’s threats and challenges, like Iran and the Gaza war, stubbornly persist following the pomp and circumstance of Trump’s “spring bling” tour, which featured eye-popping dollar figures and an offer of a luxury jumbo jet from Qatar.

MEI Senior Fellow Iulia Joja delivers a sharp and timely warning against Russia being offered a direct role in US-Iran negotiations. Far from acting as a neutral broker, Moscow wants to leverage this moment to reshape the balance of power in the Middle East. From meetings in Muscat to tightening alliances with Tehran and Beijing, Joja unpacks how Putin’s diplomacy is less about peace — and more about building up Russian influence against the US. Washington should be paying close attention.

Two recent developments present the new Syrian government with a critical opportunity to stabilize the country. First, US President Donald Trump announced plans to lift sanctions on Syria. Second, the Kurdistan Workers’ Party declared it would disband and dissolve itself — a move that will help Damascus to finalize a deal with the Syrian Democratic Forces and integrate it into the new Syrian national army. President Trump should build on this momentum and seize the opportunity to address one of the most complex remaining challenges facing Syria: the risk of a military confrontation between Turkey and Israel inside the country.

One of the strategic thrusts of the opening months of Trump’s second terms has been aimed at deepening America’s economic engagement with the leading economies of the Gulf. Thus, the first leg of his trip to the region resulted in a template for deeper US-Saudi ties.

Neoconservatives and MAGA isolationists are locked in a battle for the soul of Republican strategy. Nowhere is the split more glaring than over the Middle East: hawks view it as a proving ground for American power and allegiance to Israel, while isolationists see only endless wars that have bled America dry. Where does Trump fall in this tug-of-war?

This week, US President Donald Trump makes his inaugural visit to the Middle East since the start of his second term, traveling to Saudi Arabia, Qatar, and the United Arab Emirates on May 13-16. Amid the heightened focus on US policy toward the Middle East, MEI’s experts take stock of Trump’s trip to the Gulf, how his administration has shaped its approach to the wider region in its first several months, and how regional actors are responding to the policies coming out of Washington.

On March 10, 2025, Ahmed al-Sharaa, the president of Syria, and Mazloum Abdi, the commander-in-chief of the Syrian Democratic Forces, signed a historic agreement, ending a long-running divide between Damascus and the Democratic Autonomous Administration of North and East Syria. Now, two months after the deal was signed, how far has it progressed, and what are the main obstacles and disputes between the parties during this transitional phase?

President Donald J. Trump’s trip to the Middle East on May 13-16 comes on the heels of more than three months of whirlwind activity in US foreign policy where the region has been a higher priority than it was in the early months of the previous US administration. The US president has gained attention by proposing some provocative ideas and his team has made some signs of progress in talks with Iran, but thus far the second Trump administration has produced very few tangible advances for stability, prosperity, and progress in the Middle East. The following report assesses the US government’s actions on Middle East policy over the past three months, from late January to late April 2025.

President Donald Trump reached the 100-day mark in his second term this week seeing a sharp drop in his domestic political standing. This comes less than two weeks before Trump embarks on a key Middle East trip to the Gulf. The administration may be looking to the presidential visit as a chance to achieve some progress, but the region remains fraught with uncertainty and US policy in the Middle East rarely provides domestic political dividends.

Iran appears to be reorienting its approach to diplomatic engagement with its neighbors and the West by prioritizing the economic benefits of cooperation. A possible withdrawal of support for the Houthis is the latest significant potential outcome of Iran’s shifting stance. The following are five factors to watch for as a Tehran under duress reformulates its policies.