Iran is facing the largest demonstrations since 2022, when the death of Mahsa Amini in police custody ignited a nationwide uprising. This time, the unrest comes as the Islamic Republic is unusually exposed—still reeling from a bruising 12-day war with Israel last summer. What does this moment mean for the regime’s survival? How is this wave of protests different from those that came before? And is there anything the outside world can do to support Iran’s pro-democracy movement without backfiring?
How Damascus and the SDF came to blows in Aleppo — and what might come next
After months of building tensions, full-blown hostilities erupted between Syria’s transitional government and militia fighters linked to the Syrian Democratic Forces (SDF) in Aleppo on January 6. Through four days of fighting, government forces have now assumed full control of Syria’s second city, after expelling SDF-linked forces from its northwestern districts.
America’s dramatic capture of Venezuelan dictator Nicolas Maduro has set the stage for the conduct of America’s national security strategy in 2026. It has also raised questions.
This bonus episode of Middle East Focus features a conversation from MEI’s Virtual Briefing Series. Director of Communications Zeina Al-Shaib is joined by Distinguished Diplomatic Fellow Alan Eyre and Senior Fellow Alex Vatanka to discuss the ongoing protests in Iran. The street demonstrations, sparked by the country’s economic nosedive and at times turning violent, are the largest in three years. As regime arrests and killings of protesters have intensified, US President Donald Trump has threatened to intervene, his remarks potentially taking on a more vivid significance in light of the American military extraction over the weekend of Venezuela’s President Nicolás Maduro, an ally of Tehran. Eyre and Vatanka discuss what these latest developments mean for an Iranian regime already under intense internal and international pressure; the political impact of President Trump’s threats; the limits of Iranian President Masoud Pezeshkian’s power to de-escalate the situation at home; and how the instability inside Iran may affect the wider region.
From coalition to confrontation: Saudi-UAE rivalry in Yemen and its regional implications
The final days of 2025 marked a turning point in the Middle East, as competition between Saudi Arabia and the United Arab Emirates in Yemen spilled out into the open. Tensions between the two coalition partners, which jointly launched a military intervention in Yemen in 2015, have simmered for years and are now rapidly escalating, with far-reaching implications for both Yemen and regional security more broadly.
Iran’s Axis of Resistance after the 12-day war: Adaptation, restructuring, and reconstitution
Since Israel’s 12-day war against Iran, Tehran and its network of regional proxies and non-state allies, the so-called Axis of Resistance, have entered a phase of strategic dormancy — an outward calm concealing rearmament, financial adaptation, and ideological renewal.
US President Donald Trump is scheduled to deliver a prime time address to the nation this evening at a moment when public support for his second term has hit new lows. No matter the topic Trump chooses to frame the national conversation as America heads into the holiday season, it is worth taking a step back and reflecting on the bigger story of what has occurred in the United States in 2025 and how these dynamics affect America’s relations with the rest of the world, including the Middle East.
Unfinished business will drive the Mideast agenda in 2026
Following another year of pivotal developments and transformational change, the Middle East could be poised to turn the page on many of its long-running conflicts and sources of instability. But lasting fruits of the processes begun in 2025 will require a determined, intentional focus by regional actors and the United States. Given current trends, MEI experts weigh in on where the region may be headed in 2026.
Brian sits down with Robert Malley, a former US official best known for his role as the lead negotiator of the 2015 Joint Comprehensive Plan of Action. Malley discusses the motivations behind his new book, Tomorrow Is Yesterday: Life, Death, and the Pursuit of Peace in Israel/Palestine, and offers his assessment of American perspectives on the war in Gaza. The conversation also explores his personal background as the son of an Egyptian Jewish father and an American Jewish mother—both outspoken on the political left—and how that upbringing shaped his worldview, alongside a career spanning the Clinton, Obama, and Biden administrations.
The Trump administration has released its new National Security Strategy—and analysts say it signals a decisive break from America’s role as the leader of the free world. Instead, the document advances an openly illiberal, strongman-centered vision of power. One former U.S. official goes further, arguing the strategy doesn’t merely abandon democracy promotion—it puts Washington in the business of promoting autocracy.
What does Trump’s new National Security Strategy mean for the Middle East?
In this episode, MEI Distinguished Diplomatic Fellow Ambassador David Hale joins host Alistair Taylor to unpack the Trump administration’s new National Security Strategy (NSS). Released on December 4, the document outlines the administration’s foreign policy vision, priorities, and approach to global challenges. Ambassador Hale analyzes the new NSS and how it compares to previous US strategy documents. The conversation focuses on what the NSS means for the future of US policy in the Middle East, and how it is likely to be received by regional actors.
How Palestinian Roots Shaped an American Ambassador
Brian welcomes Ambassador (ret.) Theodore “Ted” Kattouf, who previously served as US Ambassador to Syria and the United Arab Emirates, as well as President and CEO of the leading nonprofit organization Amideast. Kattouf reflects on how his Palestinian-American background shaped his diplomatic career and worldview. The two also take time to honor the life and legacy of Paul Kattouf, Ted’s son and Brian’s high school classmate, who was murdered in 2024.
American commitment to foundational values must withstand assault by an individual
Two members of the US diplomatic corps who served in Afghanistan and are involved in the Afghan resettlement program call on Americans to uphold principles of justice and fairness when judging the person accused of shooting National Guard members in Washington, DC.
