US-Iran Nuclear Talks: A Fragile Opening for Diplomacy
Following seven years of diplomatic deadlock, Washington and Tehran have resumed nuclear negotiations — and for the first time in years, there are signs of real momentum.
Alex Vatanka, MEI Senior Fellow and author of The Battle of the Ayatollahs in Iran, joins hosts Alistair Taylor and Matthew Czekaj to analyze the current round of talks, the technical issues under discussion, and the political stakes on both sides. He explores Iran’s economic and domestic pressures, US red lines, and the role of key players like Israel, China, and Oman in shaping the negotiations.
Thinking the unthinkable: Improved US-Iran relations under Trump?
It is no surprise that both Iran and the United States have approached their first diplomatic engagement in four years with wariness. There are plenty of reasons to be skeptical about the probability of the negotiations culminating in a deal. But it would be a mistake to assume that the conditions in 2025 are the same as existed in 2015. Time is not on the Iranians’ side now and changes afoot in the Middle East and the broader global community give Iran an incentive to move toward an agreement, assuming that Washington is sincere and realistic in its negotiations with Tehran.
ISIS is on the ropes in Syria. A successful transition in Damascus could deliver a knockout blow
For much of the past two decades, ISIS has enjoyed favorable conditions in Syria, but since the fall of Bashar al-Assad’s regime in December 2024, dynamics have changed. With Assad’s departure, ISIS lost its long-standing and vitally important safe haven in Syria’s central desert and its most significant driver for recruitment. The results — so far — have been dramatic.
The first two months of Trump 2.0 in the Middle East: Hard push for elusive breakthroughs
President Donald Trump is focused on realizing two transformative breakthroughs that his predecessors failed to accomplish: an end to the Arab-Israeli conflict, centered on a tripartite US-Saudi-Israeli deal, and an agreement between the US and Iran. Both would be historic achievements. So far, however, progress in each case has proven difficult and plodding.
Iran is accumulating enough near-weapons-grade enriched uranium to build a nuclear weapon within weeks or months, not years. President Donald Trump, having withdrawn the United States in 2018 from the nuclear deal that would have postponed that possibility, is now appealing for negotiations with Tehran. But in the Middle East, the nuclear question does not concern only Iran.
Reimagining Syria: A Roadmap for Peace and Prosperity Beyond Assad
The work of the Syria Strategy Project and the considerable policy recommendations found in this report present a realistic and holistic vision for Syria’s recovery and reintegration into the international system.
US disengagement and new regional security dynamics in Afghanistan’s neighborhood
Afghanistan’s neighborhood is in the midst of a consequential restructuring of its security architecture. Key regional actors Pakistan, Afghanistan, Iran, and China have been continuing to adjust their defense plans and security partnerships to meet the growing threats posed by domestic and cross-border terrorism. At the same time, these four countries have also been looking for new ways to fill the vacuum in southern Asia left by the United States military’s departure from Afghanistan.
Normalizing regular contacts and building relationships with the Taliban leadership can offer a more effective way to hold the Islamic Emirate to account for its actions. It also gives greater promise of realizing American hopes for an Afghanistan inhospitable to global terrorists and more respectful of the human rights of its citizens.
With al-Assad gone, the risk of an ISIS resurgence grows
This perilous moment for Syria’s future comes at a moment when American foreign policy in the region could change on a dime. President-elect Donald Trump has already stated the United States should have “nothing to do” with Syria’s future. But to do nothing would give the Islamic State a chance to surge once again.
In only six days, a broad coalition of advancing opposition forces coordinated by Hayat Tahrir al-Sham has captured all of Idlib province, almost all of Aleppo province, and a sizeable stretch of northern Hama — a humiliating defeat for Bashar al-Assad and illustrative of the fragility of regime rule in Syria.
To abandon the Syria mission now would bring no meaningful benefit to the US, but it would swiftly and significantly empower America’s adversaries, like ISIS, Iran, Russia, and Assad’s regime.
Over the past month, Iran and its regional network of allies and proxies – The Axis of Resistance – has suffered a string of dramatic losses and defeats. What is the future of the Axis and its members, and what can the US and its allies do to confront and disrupt this Iranian-led network?
