Khamenei did this to himself. The US can help — without another Middle East quagmire
Last week, Iran’s Supreme Leader Ali Khamenei effectively greenlit mass killing to save his regime. His message was blunt: blood would be spilled to preserve the system. His security forces followed through, unleashing a level of violence against protesters that even by the Islamic Republic’s grim standards marks a dangerous escalation.
Iran is facing the largest demonstrations since 2022, when the death of Mahsa Amini in police custody ignited a nationwide uprising. This time, the unrest comes as the Islamic Republic is unusually exposed—still reeling from a bruising 12-day war with Israel last summer. What does this moment mean for the regime’s survival? How is this wave of protests different from those that came before? And is there anything the outside world can do to support Iran’s pro-democracy movement without backfiring?
America’s dramatic capture of Venezuelan dictator Nicolas Maduro has set the stage for the conduct of America’s national security strategy in 2026. It has also raised questions.
This bonus episode of Middle East Focus features a conversation from MEI’s Virtual Briefing Series. Director of Communications Zeina Al-Shaib is joined by Distinguished Diplomatic Fellow Alan Eyre and Senior Fellow Alex Vatanka to discuss the ongoing protests in Iran. The street demonstrations, sparked by the country’s economic nosedive and at times turning violent, are the largest in three years. As regime arrests and killings of protesters have intensified, US President Donald Trump has threatened to intervene, his remarks potentially taking on a more vivid significance in light of the American military extraction over the weekend of Venezuela’s President Nicolás Maduro, an ally of Tehran. Eyre and Vatanka discuss what these latest developments mean for an Iranian regime already under intense internal and international pressure; the political impact of President Trump’s threats; the limits of Iranian President Masoud Pezeshkian’s power to de-escalate the situation at home; and how the instability inside Iran may affect the wider region.
Iran’s political deadlock — and a way out the regime is unlikely to take
On Sunday, December 28, Iran’s latest wave of unrest began not on a university campus or in a symbolic political square, but in the very heart of the country’s economic sphere: the Grand Bazaar commercial center in downtown Tehran. What distinguishes the current moment is not simply the persistence of unrest but its emotional register. Iranian commentary increasingly describes not just hardship but a collapse of expectations of a better future.
From coalition to confrontation: Saudi-UAE rivalry in Yemen and its regional implications
The final days of 2025 marked a turning point in the Middle East, as competition between Saudi Arabia and the United Arab Emirates in Yemen spilled out into the open. Tensions between the two coalition partners, which jointly launched a military intervention in Yemen in 2015, have simmered for years and are now rapidly escalating, with far-reaching implications for both Yemen and regional security more broadly.
Iran’s Axis of Resistance after the 12-day war: Adaptation, restructuring, and reconstitution
Since Israel’s 12-day war against Iran, Tehran and its network of regional proxies and non-state allies, the so-called Axis of Resistance, have entered a phase of strategic dormancy — an outward calm concealing rearmament, financial adaptation, and ideological renewal.
Brian sits down with Robert Malley, a former US official best known for his role as the lead negotiator of the 2015 Joint Comprehensive Plan of Action. Malley discusses the motivations behind his new book, Tomorrow Is Yesterday: Life, Death, and the Pursuit of Peace in Israel/Palestine, and offers his assessment of American perspectives on the war in Gaza. The conversation also explores his personal background as the son of an Egyptian Jewish father and an American Jewish mother—both outspoken on the political left—and how that upbringing shaped his worldview, alongside a career spanning the Clinton, Obama, and Biden administrations.
This backgrounder provides an overview of the Axis of Resistance, a loosely aligned network of armed groups and state actors led and supported by Iran to project its influence and military strength across the Middle East.
Trump-MBS summit: Good feelings, real commitments, and unresolved questions
Mohammed bin Salman, the crown prince, prime minister, and main decision-maker in Saudi Arabia, left Washington and his summit with President Donald Trump with a number of promises made and commitments received. But several questions, including on shared diplomatic agenda items, the extent of civilian nuclear cooperation, and the nature of the American defense commitment to Saudi Arabia, remain unanswered.
Special Feature: A Front-Row Seat to Saudi Arabia’s Transformation
In this episode, Brian sits down with Faisal Abbas, editor-in-chief of Arab News. Abbas, who reported on Saudi Crown Prince Mohammed bin Salman’s November 18 visit to the White House, unpacks his impressions from the visit and the opportunities it presents for US-Saudi relations. The conversation also explores the Kingdom’s transformation over the past decade, its relationships with key partners including the United States, and Abbas’s recommendations for deepening the US-Saudi partnership going forward.
How Iraq’s vote will shape the next phase of US-Iran competition
For Iran, Iraq is strategic depth, political sanctuary, and economic lifeline all at once. The results of the November 11 Iraqi elections will decide who in Baghdad controls the budgetary levers, internal security appointments, and committees that could codify, or constrain, Iraq’s Iran-backed militias.
On November 18, Saudi Crown Prince Mohammed bin Salman is scheduled to make his first trip to Washington since 2018. In a new MEI Policy Memo, Daniel Benaim breaks down why it matters for the US and the relevant policy considerations.
On November 18, Saudi Crown Prince Mohammed
bin Salman (MBS) is scheduled to make his first trip to Washington since 2018. President Donald Trump has doubled down on the Gulf from the outset of his second term, making Riyadh his first planned overseas trip and reorienting ties around major artificial intelligence (AI) and investment deals. MBS’s visit will test whether both sides can translate ambitious pledges into concrete outcomes. Significant upgrades in defense and security are expected, with movement possible on semiconductor sales and nuclear cooperation. Behind the ambitions, harder questions about Saudi-Israeli normalization and alignment in a rapidly changing region loom as important Oval Office topics.
Divisions at home hinder America’s ambitions abroad
Over the past week, US President Donald Trump made an extended trip to Asia and threatened military actions against Latin American and African countries. But despite his administration’s continuing ambitions in the Middle East region, few major breakthroughs are expected there in the immediate future due to the government shutdown and unilateral cuts to national security infrastructure.
