This report considers the lack of Palestinian political agency as a driver of regional insecurity that must be resolved before wider conflicts can be settled. The author analyses the conditions that contributed to the destruction of Palestinian political capacity, including Israeli policies, Palestinian shortcomings, and exploitation by Iran, and makes recommendations for an Arab strategic initiative.
Iran’s New Grand Design: The Next Evolution of the Axis of Resistance
Iran is transforming its Axis of Resistance into a decentralized, Yemen-centered network that leverages the Houthis to threaten both the Strait of Hormuz and the Bab el-Mandeb, extending Tehran’s coercive reach over the world’s key maritime chokepoints and reshaping the post-war balance in the Middle East and Red Sea.
This bonus episode of Middle East Focus features a conversation from MEI’s Virtual Briefing Series. Director of Communications Zeina Al-Shaib is joined by Distinguished Diplomatic Fellow Alan Eyre and Senior Fellow Alex Vatanka to discuss the ongoing protests in Iran. The street demonstrations, sparked by the country’s economic nosedive and at times turning violent, are the largest in three years. As regime arrests and killings of protesters have intensified, US President Donald Trump has threatened to intervene, his remarks potentially taking on a more vivid significance in light of the American military extraction over the weekend of Venezuela’s President Nicolás Maduro, an ally of Tehran. Eyre and Vatanka discuss what these latest developments mean for an Iranian regime already under intense internal and international pressure; the political impact of President Trump’s threats; the limits of Iranian President Masoud Pezeshkian’s power to de-escalate the situation at home; and how the instability inside Iran may affect the wider region.
Iran’s political deadlock — and a way out the regime is unlikely to take
On Sunday, December 28, Iran’s latest wave of unrest began not on a university campus or in a symbolic political square, but in the very heart of the country’s economic sphere: the Grand Bazaar commercial center in downtown Tehran. What distinguishes the current moment is not simply the persistence of unrest but its emotional register. Iranian commentary increasingly describes not just hardship but a collapse of expectations of a better future.
From coalition to confrontation: Saudi-UAE rivalry in Yemen and its regional implications
The final days of 2025 marked a turning point in the Middle East, as competition between Saudi Arabia and the United Arab Emirates in Yemen spilled out into the open. Tensions between the two coalition partners, which jointly launched a military intervention in Yemen in 2015, have simmered for years and are now rapidly escalating, with far-reaching implications for both Yemen and regional security more broadly.
Iran’s Axis of Resistance after the 12-day war: Adaptation, restructuring, and reconstitution
Since Israel’s 12-day war against Iran, Tehran and its network of regional proxies and non-state allies, the so-called Axis of Resistance, have entered a phase of strategic dormancy — an outward calm concealing rearmament, financial adaptation, and ideological renewal.
The Middle East Institute hosted Dr. Gregory Gause, Ambassador Michael Ratney, and Dr. Karen Young for an assessment of Saudi policy and the US-Saudi relationship in the wake of the MBS visit.
US President Donald Trump is scheduled to deliver a prime time address to the nation this evening at a moment when public support for his second term has hit new lows. No matter the topic Trump chooses to frame the national conversation as America heads into the holiday season, it is worth taking a step back and reflecting on the bigger story of what has occurred in the United States in 2025 and how these dynamics affect America’s relations with the rest of the world, including the Middle East.
Unfinished business will drive the Mideast agenda in 2026
Following another year of pivotal developments and transformational change, the Middle East could be poised to turn the page on many of its long-running conflicts and sources of instability. But lasting fruits of the processes begun in 2025 will require a determined, intentional focus by regional actors and the United States. Given current trends, MEI experts weigh in on where the region may be headed in 2026.
Brian sits down with Robert Malley, a former US official best known for his role as the lead negotiator of the 2015 Joint Comprehensive Plan of Action. Malley discusses the motivations behind his new book, Tomorrow Is Yesterday: Life, Death, and the Pursuit of Peace in Israel/Palestine, and offers his assessment of American perspectives on the war in Gaza. The conversation also explores his personal background as the son of an Egyptian Jewish father and an American Jewish mother—both outspoken on the political left—and how that upbringing shaped his worldview, alongside a career spanning the Clinton, Obama, and Biden administrations.
The oldest peer-reviewed publication dedicated to the study of the modern Middle East, MEI’s flagship journal covers politics, society, and culture in the region.
