Iran is facing the largest demonstrations since 2022, when the death of Mahsa Amini in police custody ignited a nationwide uprising. This time, the unrest comes as the Islamic Republic is unusually exposed—still reeling from a bruising 12-day war with Israel last summer. What does this moment mean for the regime’s survival? How is this wave of protests different from those that came before? And is there anything the outside world can do to support Iran’s pro-democracy movement without backfiring?
America’s dramatic capture of Venezuelan dictator Nicolas Maduro has set the stage for the conduct of America’s national security strategy in 2026. It has also raised questions.
This bonus episode of Middle East Focus features a conversation from MEI’s Virtual Briefing Series. Director of Communications Zeina Al-Shaib is joined by Distinguished Diplomatic Fellow Alan Eyre and Senior Fellow Alex Vatanka to discuss the ongoing protests in Iran. The street demonstrations, sparked by the country’s economic nosedive and at times turning violent, are the largest in three years. As regime arrests and killings of protesters have intensified, US President Donald Trump has threatened to intervene, his remarks potentially taking on a more vivid significance in light of the American military extraction over the weekend of Venezuela’s President Nicolás Maduro, an ally of Tehran. Eyre and Vatanka discuss what these latest developments mean for an Iranian regime already under intense internal and international pressure; the political impact of President Trump’s threats; the limits of Iranian President Masoud Pezeshkian’s power to de-escalate the situation at home; and how the instability inside Iran may affect the wider region.
Iran’s political deadlock — and a way out the regime is unlikely to take
On Sunday, December 28, Iran’s latest wave of unrest began not on a university campus or in a symbolic political square, but in the very heart of the country’s economic sphere: the Grand Bazaar commercial center in downtown Tehran. What distinguishes the current moment is not simply the persistence of unrest but its emotional register. Iranian commentary increasingly describes not just hardship but a collapse of expectations of a better future.
Iran’s Axis of Resistance after the 12-day war: Adaptation, restructuring, and reconstitution
Since Israel’s 12-day war against Iran, Tehran and its network of regional proxies and non-state allies, the so-called Axis of Resistance, have entered a phase of strategic dormancy — an outward calm concealing rearmament, financial adaptation, and ideological renewal.
Brian sits down with Robert Malley, a former US official best known for his role as the lead negotiator of the 2015 Joint Comprehensive Plan of Action. Malley discusses the motivations behind his new book, Tomorrow Is Yesterday: Life, Death, and the Pursuit of Peace in Israel/Palestine, and offers his assessment of American perspectives on the war in Gaza. The conversation also explores his personal background as the son of an Egyptian Jewish father and an American Jewish mother—both outspoken on the political left—and how that upbringing shaped his worldview, alongside a career spanning the Clinton, Obama, and Biden administrations.
This backgrounder provides an overview of the Axis of Resistance, a loosely aligned network of armed groups and state actors led and supported by Iran to project its influence and military strength across the Middle East.
How Iraq’s vote will shape the next phase of US-Iran competition
For Iran, Iraq is strategic depth, political sanctuary, and economic lifeline all at once. The results of the November 11 Iraqi elections will decide who in Baghdad controls the budgetary levers, internal security appointments, and committees that could codify, or constrain, Iraq’s Iran-backed militias.
Top photo:
TEHRAN, IRAN – MARCH 10: Smoke rises among the residential buildings following an Israeli attack on Tehran, Iran on March 10, 2026. (Photo by Fatemeh Bahrami/Anadolu via Getty Images)
