America’s New Defense Strategy — and What It Means for Iran
Hosts Alistair Taylor and Matthew Czekaj are joined by MEI Distinguished Military Fellow Mick Mulroy to discuss the Trump administration’s new National Defense Strategy (NDS) and its implications for the Middle East. While serving as the Deputy Assistant Secretary of Defense (DASD) for the Middle East from 2017 to 2019, Mulroy helped prepare the 2018 NDS, giving him an insider perspective on US defense planning. Together, Taylor, Czekaj, and Mulroy unpack what the new strategy means for US priorities globally and for the Middle East in particular, including how it could be reflected in a potentially looming military strike on Iran.
Ambiguous Uncertainties: Phase Two of Trump’s Plan for Gaza
MEI Senior Fellow Lucy Kurtzer-Ellenbogen joins hosts Alistair Taylor and Matthew Czekaj to discuss the latest developments in Gaza. Nearly four months after the Israeli government and Hamas agreed to President Donald Trump’s 20-point plan, Washington has announced that phase two of the process is now underway. Kurtzer-Ellenbogen, Taylor, and Czekaj examine the humanitarian situation in the devastated coastal strip, assess what phase two could entail, break down how international actors are responding, and explore what would need to happen to realize the plan’s aspirations.
The Pakistan-Afghanistan conflict: A strategic concern for the US
Pakistan’s relationship with the Afghan Taliban has shifted from open sponsorship in the 1990s to a silent partnership following 2001 to alienation and belligerence since 2021. Their current conflict, which comes at great cost to both countries and seems to have no easy military or political resolution, also poses a threat to the stability and prosperity of neighboring states. Although American strategic interests in the region greatly diminished following the United States’ military withdrawal from Afghanistan in August 2021, the region’s altered political dynamics have prompted a growing American engagement with Pakistan and tentatively with Afghanistan. At the same time, the US has become a factor in how both Islamabad and Kabul have come to form their national security strategies.
Venezuela’s Shadow Over MENA: Perceptions and Precedents
MEI Vice President for Policy Ken Pollack joins hosts Alistair Taylor and Matthew Czekaj to explore what the precedent set by the Trump administration’s military capture of Venezuelan President Nicolás Maduro could mean for US policy in the Middle East — particularly in light of ongoing anti-regime protests in Iran. The conversation unpacks the reverberations of Operation Absolute Resolve, Washington’s options for and potential consequences of responding to the Iranian regime’s brutal crackdown, regional perceptions of recent US actions and stated objectives, and broader questions around the direction of the Trump administration’s evolving grand strategy.
This bonus episode of Middle East Focus features a conversation from MEI’s Virtual Briefing Series. Director of Communications Zeina Al-Shaib is joined by Distinguished Diplomatic Fellow Alan Eyre and Senior Fellow Alex Vatanka to discuss the ongoing protests in Iran. The street demonstrations, sparked by the country’s economic nosedive and at times turning violent, are the largest in three years. As regime arrests and killings of protesters have intensified, US President Donald Trump has threatened to intervene, his remarks potentially taking on a more vivid significance in light of the American military extraction over the weekend of Venezuela’s President Nicolás Maduro, an ally of Tehran. Eyre and Vatanka discuss what these latest developments mean for an Iranian regime already under intense internal and international pressure; the political impact of President Trump’s threats; the limits of Iranian President Masoud Pezeshkian’s power to de-escalate the situation at home; and how the instability inside Iran may affect the wider region.
Iran’s Axis of Resistance after the 12-day war: Adaptation, restructuring, and reconstitution
Since Israel’s 12-day war against Iran, Tehran and its network of regional proxies and non-state allies, the so-called Axis of Resistance, have entered a phase of strategic dormancy — an outward calm concealing rearmament, financial adaptation, and ideological renewal.
A year after Assad’s fall, Syria faces a pivotal moment. Washington must lead.
One year after the fall of the Assad regime, Syria is still in very fragile phase of its transition to a new political order. The country faces monumental reconstruction challenges, estimated in the hundreds of billions of dollars, well beyond the capabilities of the new Syrian government. Without sustained American leadership and investment, Syria’s transition will be slow, fragile, and dangerously reversible.
This backgrounder provides an overview of the Axis of Resistance, a loosely aligned network of armed groups and state actors led and supported by Iran to project its influence and military strength across the Middle East.
This backgrounder provides an overview of the history of Hamas, its ideology and leadership, military capabilities and goals, the October 7 attack, relevant US government policies and legislation, and the group’s future in Gaza.
The United States plans to submit a resolution on Gaza to the United Nations Security Council (UNSC) by the end of November. Reportedly, thelatest draftendorses President Donald Trump’s 20-point plan, recognizes the Board of Peace (BoP) as a “transitional governance administration,” and authorizes the BoP to establish an International Stabilization Force (ISF). The UN resolution is a first stepto achieving buy-in from potential ISF contributors. In turn, a viable ISF will be one key to moving beyond the cease-fire to securing the 20-point plan’s envisioned Hamas disarmament, further Israeli military withdrawal, and a path to Palestinian governance. The US faces several dilemmas as it seeks to transition from cease-fire to stabilization and beyond.
The legitimacy trap: How international institutions sustain the Houthis’ hold on Yemen
For years, the prevailing assumption was that the Houthis’ survival depended on battlefield victories and Iranian support. Both are essential, but there is a third critical and often overlooked factor: the weaponization of international engagement. In a pattern that continues to repeat itself, engagement without accountability strengthens rather than moderates Houthi behavior.
Will Syria join the Global Coalition to Defeat ISIS?
The joint al-Dumayr operation in mid-October was the fifth instance of coordination between the Global Coalition to Defeat ISIS and the Syrian government to confront the Islamic State, amid Western calls for Damascus to officially join the international effort. What’s at stake and what are the potential scenarios moving forward?
The central challenge facing Lebanon today is whether the country will graduate to functional statehood or continue struggling to survive. Yet with Lebanese officials now insisting that the state “monopolize arms” and become the decisive arbiter on matters of war and peace, a relevant question arises: Where, territorially, does Lebanon begin and end?
The October 2025 cease-fire and hostage-release deal that ended the Israel-Hamas conflict marks the beginning of a complicated post-war phase. The agreement has created important opportunities to advance stability in the Middle East and build a lasting and sustainable peace marked by enhanced regional security and integration, but there are considerable risks to manage. Achieving these goals will require coordinated international action along multiple lines of effort: security, rule of law, recovery and reconstruction, responsive governance, and steady and focused diplomacy to build confidence among key parties.
