This bonus episode of Middle East Focus features an excerpt from a recent MEI Virtual Briefing recorded on January 20. Director of Communications Zeina Al-Shaib is joined by MEI Affiliate Fatima Abo Alasrar and Associate Fellow F. Gregory Gause III to discuss the dramatically changing dynamics in Yemen’s civil war. Last month, Yemen emerged as a focal point of rising tensions between Saudi Arabia and the United Arab Emirates. The Southern Transitional Council, a UAE-backed southern separatist movement, has disbanded in recent weeks, following fierce clashes with Saudi-backed forces. In the conversation, Alasrar and Gause analyze the political, security, and socio-economic shifts affecting Yemen’s internal dynamics and what all this means for regional stability.
Brian sits down with Behnam Taleblu, Senior Fellow at the Foundation for Defense of Democracies, to unpack the ongoing protests in Iran and what this moment reveals about the long struggle between the state and the street. They discuss the regime’s brutal crackdown, the prospect of US intervention, and what both could mean for the future of the Islamic Republic. The episode centers on agency, imagination, and the possibilities facing Iranians at a critical juncture in the country’s history.
Iran’s coming reckoning: Regime collapse is likely — democracy is not
The collapse of the Iranian regime in its present form now seems more plausible than its survival as a functioning state. Yet the emergence of a democratic Iran remains far from certain. Between these two outcomes lies a volatile and dangerous middle ground. But much will depend on four factors.
From Peripheries to Tehran: Iran’s New Geography of Protest
Iran is once again in the midst of nationwide unrest. Protests that erupted in late 2025—initially driven by an acute economic crisis rapidly spreading across the entire country—are ongoing. Whether this latest wave culminates in revolutionary rupture, regime adaptation, or a familiar cycle of repression and exhaustion remains uncertain. What is already clear, however, is that the structural forces animating the unrest extend far beyond the present.
At the heart of Iran’s protests lies a set of sharp and enduring regional disparities that have long shaped patterns of development, political control, and social mobilization. These center–periphery divides have repeatedly rendered Iran’s border provinces more vulnerable to deprivation, marginalization, and protest, while allowing the political and economic core to absorb shocks with greater resilience. Today, those divides are under unprecedented strain, as economic hardship is no longer confined to the margins but increasingly shared across the country.
Potential US military strikes on Iran: This won’t be another 12-Day War
President Donald Trump has sharply warned the Iranian regime to halt its brutal crackdown on protesters. Amid speculation that the US is preparing for military action in Iran, Washington should take the lessons and fundamentally different context of its successful June 2025 operation against the Islamic Republic into account as it plans for how to respond.
Iran protests seem different. They may lead to real change.
People are not protesting because they suddenly discovered activism. They are protesting because the habits of coping and waiting for conditions to improve have finally stopped working.
Venezuela’s Shadow Over MENA: Perceptions and Precedents
MEI Vice President for Policy Ken Pollack joins hosts Alistair Taylor and Matthew Czekaj to explore what the precedent set by the Trump administration’s military capture of Venezuelan President Nicolás Maduro could mean for US policy in the Middle East — particularly in light of ongoing anti-regime protests in Iran. The conversation unpacks the reverberations of Operation Absolute Resolve, Washington’s options for and potential consequences of responding to the Iranian regime’s brutal crackdown, regional perceptions of recent US actions and stated objectives, and broader questions around the direction of the Trump administration’s evolving grand strategy.
Khamenei did this to himself. The US can help — without another Middle East quagmire
Last week, Iran’s Supreme Leader Ali Khamenei effectively greenlit mass killing to save his regime. His message was blunt: blood would be spilled to preserve the system. His security forces followed through, unleashing a level of violence against protesters that even by the Islamic Republic’s grim standards marks a dangerous escalation.
Iran is facing the largest demonstrations since 2022, when the death of Mahsa Amini in police custody ignited a nationwide uprising. This time, the unrest comes as the Islamic Republic is unusually exposed—still reeling from a bruising 12-day war with Israel last summer. What does this moment mean for the regime’s survival? How is this wave of protests different from those that came before? And is there anything the outside world can do to support Iran’s pro-democracy movement without backfiring?
America’s dramatic capture of Venezuelan dictator Nicolas Maduro has set the stage for the conduct of America’s national security strategy in 2026. It has also raised questions.
This bonus episode of Middle East Focus features a conversation from MEI’s Virtual Briefing Series. Director of Communications Zeina Al-Shaib is joined by Distinguished Diplomatic Fellow Alan Eyre and Senior Fellow Alex Vatanka to discuss the ongoing protests in Iran. The street demonstrations, sparked by the country’s economic nosedive and at times turning violent, are the largest in three years. As regime arrests and killings of protesters have intensified, US President Donald Trump has threatened to intervene, his remarks potentially taking on a more vivid significance in light of the American military extraction over the weekend of Venezuela’s President Nicolás Maduro, an ally of Tehran. Eyre and Vatanka discuss what these latest developments mean for an Iranian regime already under intense internal and international pressure; the political impact of President Trump’s threats; the limits of Iranian President Masoud Pezeshkian’s power to de-escalate the situation at home; and how the instability inside Iran may affect the wider region.
Yemen’s Southern Front: Strategic Leverage, Fragmentation, and Regional Risk
Beginning in early December 2025, UAE-backed Southern Transitional Council (STC) forces launched an offensive in eastern Yemen, seizing Seiyun and key military and administrative sites across Wadi Hadhramaut before advancing into al-Mahrah, as Saudi-aligned tribal and government units withdrew under mounting political and military pressure.
Iran’s political deadlock — and a way out the regime is unlikely to take
On Sunday, December 28, Iran’s latest wave of unrest began not on a university campus or in a symbolic political square, but in the very heart of the country’s economic sphere: the Grand Bazaar commercial center in downtown Tehran. What distinguishes the current moment is not simply the persistence of unrest but its emotional register. Iranian commentary increasingly describes not just hardship but a collapse of expectations of a better future.
From coalition to confrontation: Saudi-UAE rivalry in Yemen and its regional implications
The final days of 2025 marked a turning point in the Middle East, as competition between Saudi Arabia and the United Arab Emirates in Yemen spilled out into the open. Tensions between the two coalition partners, which jointly launched a military intervention in Yemen in 2015, have simmered for years and are now rapidly escalating, with far-reaching implications for both Yemen and regional security more broadly.
Iran’s Axis of Resistance After the 12-day War: Adaptation, Restructuring, and Reconstitution
Since Israel’s 12-day war against Iran, Tehran and its network of regional proxies and non-state allies, the so-called Axis of Resistance, have entered a phase of strategic dormancy — an outward calm concealing rearmament, financial adaptation, and ideological renewal.
