Research & Commentary Results

Following seven years of diplomatic deadlock, Washington and Tehran have resumed nuclear negotiations — and for the first time in years, there are signs of real momentum.

Alex Vatanka, MEI Senior Fellow and author of The Battle of the Ayatollahs in Iran, joins hosts Alistair Taylor and Matthew Czekaj to analyze the current round of talks, the technical issues under discussion, and the political stakes on both sides. He explores Iran’s economic and domestic pressures, US red lines, and the role of key players like Israel, China, and Oman in shaping the negotiations.

The spotlight on US policy in the Middle East remains focused on talks with Iran, with a third round set for Oman this coming weekend after discussions in Rome on April 19 offered some signs of progress. But a growing humanitarian crisis in the Gaza Strip and the stalled efforts to safely return hostages held by Hamas remain the biggest challenges that President Donald Trump’s administration has yet to address successfully.

President Donald Trump wants a deal with Iran. Russia has offered to mediate. But an agreement negotiated by Moscow would turn the Middle East upside down as well as negate years of Western efforts to impede and deter further aggression by the Kremlin.

On April 12, the United States and Iran wrapped up their first round of renewed diplomatic talks in Muscat, with round two set for April 19, in Rome. In the interim, Iranian Foreign Minister Abbas Araghchi is in Moscow to coordinate with the Russians. But the real breakthrough will not come from nuclear talks alone — it will require confronting the region’s most explosive fault line: the Iranian-Israeli standoff. Russia claims it can help.

It is no surprise that both Iran and the United States have approached their first diplomatic engagement in four years with wariness. There are plenty of reasons to be skeptical about the probability of the negotiations culminating in a deal. But it would be a mistake to assume that the conditions in 2025 are the same as existed in 2015. Time is not on the Iranians’ side now and changes afoot in the Middle East and the broader global community give Iran an incentive to move toward an agreement, assuming that Washington is sincere and realistic in its negotiations with Tehran.

This article is published as part of the Perry World House workshop “U.S.-Iran Relations Under Trump 2.0: Lessons Learned and Likely Scenarios.”

The biggest development this past week in the Middle East policy of Trump’s second administration was the initiation of talks between the United States and Iran. This small sign of hope for diplomatic progress comes at a time when the administration continues to implement an assertive and unpredictable economic unilateralism that has roiled global markets and reduced trust and confidence between the United States and most close international partners. Brian Katulis unpacks three things to watch closely as Trump’s Iran policy evolves and his broader national security approach unfolds.

For much of the past two decades, ISIS has enjoyed favorable conditions in Syria, but since the fall of Bashar al-Assad’s regime in December 2024, dynamics have changed. With Assad’s departure, ISIS lost its long-standing and vitally important safe haven in Syria’s central desert and its most significant driver for recruitment. The results — so far — have been dramatic.

US President Donald Trump surprised Israeli Prime Minister Benjamin Netanyahu by publicly announcing “direct” talks between the United States and Iran set to take place later this week. The American president also unleashed global economic uncertainty by announcing simultaneous, unexpectedly high tariffs on dozens of countries around the world — including a 17% duty on Israel — and kicking off an escalating global trade war.

أكد الرئيس دونالد ترامب هذا الأسبوع أنه يخطط للسفر إلى المملكة العربية السعودية ودول أخرى في الشرق الأوسط في أواخر الربيع الحالي. وستسلط هذه الزيارة الضوء على المنطقة في وقت تركز فيه أولويات ترامب على الشؤون الداخلية وعلى أسلوبه الفريد في الحرب الاقتصادية.

يركز الرئيس دونالد ترامب على تحقيق إنجازين تحويليين فشل أسلافه في تحقيقهما: إنهاء الصراع العربي الإسرائيلي، الذي يتمحور حول اتفاق ثلاثي بين الولايات المتحدة والسعودية وإسرائيل، واتفاق بين الولايات المتحدة وإيران. وكلاهما سيكون إنجازًا تاريخيًا. لكن حتى الآن، ثبت أن التقدم في كلتا الحالتين صعب ومتعثر.

President Masoud Pezeshkian might be the loneliest man in Iran. Just eight months into his term in office, he is already losing the support of those who once championed him. While the Iranian presidency is a thankless job, Pezeshkian is not helping his own case.

كشفت المحادثة المسربة على تطبيق Signal بين كبار المسؤولين في الإدارة الأمريكية حول الضربات العسكرية ضد الحوثيين عن المشاكل الأساسية في نهج ترامب 2.0 الناشئ للأمن القومي: ميل قوي إلى إعطاء الأولوية للتكتيكات والدعاية في إدارة شؤون الدولة دون إطار استراتيجي واضح وعملي للتعامل مع أكبر التحديات في العالم والشرق الأوسط.

تقوم إيران بتخزين ما يكفي من اليورانيوم المخصب القريب من الدرجة العسكرية لصنع سلاح نووي في غضون أسابيع أو أشهر، وليس سنوات. والرئيس دونالد ترامب، الذي انسحب في عام 2018 من الاتفاق النووي الذي كان من شأنه تأجيل هذه الإمكانية، يناشد الآن إجراء مفاوضات مع طهران. لكن في الشرق الأوسط، لا تقتصر المسألة النووية على إيران وحدها.

عززت إدارة الرئيس دونالد ترامب استخدامها للقوة العسكرية في الشرق الأوسط الأسبوع الماضي، في الوقت الذي اتخذت فيه المزيد من الخطوات لتفكيك المؤسسات الأمريكية الأساسية لتعزيز السلام والاستقرار من خلال الدبلوماسية.