Salam Kawakibi

President Donald J. Trump’s trip to the Middle East on May 13-16 comes on the heels of more than three months of whirlwind activity in US foreign policy where the region has been a higher priority than it was in the early months of the previous US administration. The US president has gained attention by proposing some provocative ideas and his team has made some signs of progress in talks with Iran, but thus far the second Trump administration has produced very few tangible advances for stability, prosperity, and progress in the Middle East. The following report assesses the US government’s actions on Middle East policy over the past three months, from late January to late April 2025.

As the EU prepares for its annual review of sanctions imposed on Syria, it faces a moment of reckoning — an opportunity to demonstrate whether its policies not only continue to be principled and legal, but also in line with its strategic interests. They no longer serve the purpose for which they were designed, and the EU should let the entire sanctions regime on Syria collapse unconditionally and immediately.

In this wide-ranging conversation, Ambassador James Jeffrey joins host Brian Katulis to unpack the Trump administration’s early moves in its second term and what they signal for US foreign policy in the Middle East.

As Saudi Arabia accelerates its transformation into a global technology powerhouse, the United States has a pivotal opportunity to redefine its partnership with the kingdom. Moving beyond the traditional oil-for-security framework, a new partnership centered on artificial intelligence and digital infrastructure can anchor US-Saudi relations in the 21st century.​

President Donald Trump reached the 100-day mark in his second term this week seeing a sharp drop in his domestic political standing. This comes less than two weeks before Trump embarks on a key Middle East trip to the Gulf. The administration may be looking to the presidential visit as a chance to achieve some progress, but the region remains fraught with uncertainty and US policy in the Middle East rarely provides domestic political dividends.

Iran appears to be reorienting its approach to diplomatic engagement with its neighbors and the West by prioritizing the economic benefits of cooperation. A possible withdrawal of support for the Houthis is the latest significant potential outcome of Iran’s shifting stance. The following are five factors to watch for as a Tehran under duress reformulates its policies.

The arrest of Istanbul Mayor Ekrem İmamoğlu has sparked the largest wave of public protests in Turkey in over a decade, signaling a potential turning point in the country’s political trajectory. As the opposition rallies support and President Erdoğan intensifies his crackdown, what lies ahead for Turkish democracy, the Kurdish peace process, and the broader political landscape? MEI Senior Fellow Gonul Tol joins host Alistair Taylor to unpack the growing unrest, the strategic stakes for Erdoğan’s ruling coalition, and the mobilization of a new generation of political activists.

As President Trump prepares for his visit to Saudi Arabia in May, MEI’s F. Gregory Gause, III unpacks the evolving Saudi-American relationship. Compared to his first term, Trump faces a more volatile Middle East and a Crown Prince Mohammed bin Salman whose calculations have fundamentally shifted. The new regional landscape has directly reshaped MBS’s priorities toward regional stability, cautious Iran relations, and economic transformation through Vision 2030. Discover what challenges await as these two leaders navigate complex dynamics, oil markets, and the fallout from the Gaza War.

Ukraine faces a pivotal year in its fight against Russian aggression — and for its democratic future. With fears mounting that President Trump could abandon peace talks with Kyiv and Moscow, the risk grows that US disengagement could tip the balance toward Russia and fracture the global democratic order.

The chaotic US military pullout from Afghanistan in August 2021 became a hot campaign issue in the 2024 presidential election and continues to echo today. President Donald Trump, who set the withdrawal in motion during his first term in office, repeatedly criticized President Joe Biden’s administration for leaving behind billions of dollars of military equipment. Also left behind were tens of thousands of Afghans, and their family members, who faced retribution for assisting US forces in the fight against the Taliban.

Following seven years of diplomatic deadlock, Washington and Tehran have resumed nuclear negotiations — and for the first time in years, there are signs of real momentum.

Alex Vatanka, MEI Senior Fellow and author of The Battle of the Ayatollahs in Iran, joins hosts Alistair Taylor and Matthew Czekaj to analyze the current round of talks, the technical issues under discussion, and the political stakes on both sides. He explores Iran’s economic and domestic pressures, US red lines, and the role of key players like Israel, China, and Oman in shaping the negotiations.

The spotlight on US policy in the Middle East remains focused on talks with Iran, with a third round set for Oman this coming weekend after discussions in Rome on April 19 offered some signs of progress. But a growing humanitarian crisis in the Gaza Strip and the stalled efforts to safely return hostages held by Hamas remain the biggest challenges that President Donald Trump’s administration has yet to address successfully.

In this episode of Taking the Edge off the Middle East, Brian Katulis sits down with Toni Verstandig, former Deputy Assistant Secretary of State for Near Eastern Affairs and current board member at the Middle East Institute. Three months into the second Trump administration, they assess how the White House is reshaping US policy in the Middle East—what’s changed, what’s stayed the same, and what risks lie ahead. Verstandig reflects on lessons from her years working on the Israeli-Palestinian peace process during the Clinton era, offering both poignant stories and policy insights from a time when diplomacy looked very different. They also discuss how think tanks like MEI are stepping up at a moment when institutions like USIP and the Wilson Center are under fire.

President Donald Trump wants a deal with Iran. Russia has offered to mediate. But an agreement negotiated by Moscow would turn the Middle East upside down as well as negate years of Western efforts to impede and deter further aggression by the Kremlin.